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WR - Win Ratio Analysis of Composite Time-to-Event Outcomes

Implements various win ratio methodologies for composite endpoints of death and non-fatal events, including the (stratified) proportional win-fractions (PW) regression models (Mao and Wang, 2020 <doi:10.1111/biom.13382>), (stratified) two-sample tests with possibly recurrent nonfatal event, and sample size calculation for standard win ratio test (Mao et al., 2021 <doi:10.1111/biom.13501>).

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5.53 score 56 scripts 235 downloads

rmt - Restricted Mean Time in Favor of Treatment

Contains inferential and graphical routines for comparing two treatment arms in terms of the restricted mean time in favor of treatment.

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4.40 score 25 scripts 137 downloads

WA - While-Alive Loss Rate for Recurrent Event in the Presence of Death

Contains inferential and graphical routines for multi-group analysis of while-alive loss (or event) rate for possibly recurrent nonfatal event in the presence of death.

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4.00 score 8 scripts 182 downloads

poset - Analysis of Partially Ordered Data

Win ratio approach to partially ordered data, such as multivariate ordinal responses under product (consensus) or prioritized order. Two-sample tests and multiplicative regression models are implemented (Mao, 2024).

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4.00 score 2 stars 4 scripts 244 downloads

Wcompo - Semiparametric Proportional Means Regression of Weighted Composite Endpoint

Implements inferential and graphic procedures for the semiparametric proportional means regression of weighted composite endpoint of recurrent event and death (Mao and Lin, 2016, <doi:10.1093/biostatistics/kxv050>).

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2.08 score 12 scripts 265 downloads

grpseq - Group Sequential Analysis of Clinical Trials

Design of group sequential trials, including non-binding futility analysis at multiple time points (Gallo, Mao, and Shih, 2014, <doi:10.1080/10543406.2014.932285>).

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2.00 score 6 scripts 266 downloads